Sivaraman Dandapani

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 226 citations

Drug Targeting, Small-molecule Probes, Natural Sciences +8

An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

Lisa A. Marcaurelle, Eamon Comer, Sivaraman Dandapani et al. · Journal of the American Chemical Society · 2010 · 212 citations · Full text

Combinatorial Chemistry, Aldol-based Build/couple/pair, Stereochemical Dependencies +19

Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets

Sivaraman Dandapani, Lisa A. Marcaurelle · Nature Chemical Biology · 2010 · 206 citations

Drug Target, Chemical Analysis, Natural Sciences +8

Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Longqin Hu, Sadagopan Magesh, Lin Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 193 citations · Full text

Protein Function, Signal Transduction, Biochemistry +9

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

Michel Weïwer, James Spoonamore, Jingqiang Wei et al. · ACS Medicinal Chemistry Letters · 2012 · 138 citations · Full text

Kinase-selectivity Profiles, Cell Death, Cancer Biology +21