Lisa A. Marcaurelle

Identifying the proteins to which small-molecule probes and drugs bind in cells

Shao‐En Ong, Monica Schenone, Adam A. Margolin et al. · Proceedings of the National Academy of Sciences · 2009 · 307 citations · Full text

An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

Lisa A. Marcaurelle, Eamon Comer, Sivaraman Dandapani et al. · Journal of the American Chemical Society · 2010 · 212 citations · Full text

Combinatorial Chemistry, Aldol-based Build/couple/pair, Stereochemical Dependencies +19

Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets

Sivaraman Dandapani, Lisa A. Marcaurelle · Nature Chemical Biology · 2010 · 206 citations

Drug Target, Chemical Analysis, Natural Sciences +8

DNA-encoded chemical libraries

Alexander L. Satz, Andreas Brunschweiger, Mark E. Flanagan et al. · Nature Reviews Methods Primers · 2022 · 157 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Natural Sciences +5

Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries

Jason T. Lowe, Maurice D. Lee, Lakshmi B. Akella et al. · The Journal of Organic Chemistry · 2012 · 135 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Lead Identification +18