Adam A. Margolin

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.5K citations

Medicine, Oncology, Pharmacology +15

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

Adam A. Margolin, Ilya Nemenman, Katia Basso et al. · Columbia Academic Commons (Columbia University) · 2006 · 2.4K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Reverse engineering of regulatory networks in human B cells

Katia Basso, Adam A. Margolin, Gustavo Stolovitzky et al. · Nature Genetics · 2005 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +16

The evolutionary history of 2,658 cancers

Moritz Gerstung, Clemency Jolly, Ignaty Leshchiner et al. · Nature · 2020 · 1.1K citations · Full text

Medicine, Genetics, Oncology +17

NOTCH1 directly regulates <i>c-MYC</i> and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Teresa Palomero, Wei Keat Lim, Duncan T. Odom et al. · Proceedings of the National Academy of Sciences · 2006 · 822 citations · Full text

Medicine, Cancer Biology, Molecular Biology +17