Sadagopan Magesh

Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Longqin Hu, Sadagopan Magesh, Lin Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 193 citations · Full text

Protein Function, Signal Transduction, Biochemistry +9

Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: Selective inhibitors of lysosomal sialidase (NEU1)

Sadagopan Magesh, Setsuko Moriya, Tohru Suzuki et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 81 citations · Full text

Biochemistry, Antiparasitic Agent, Medicine +12

Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: Hints for the design of selective NEU3 inhibitors

Sadagopan Magesh, Tohru Suzuki, Taeko Miyagi et al. · Journal of Molecular Graphics and Modelling · 2006 · 73 citations

Crystal Structure, Biochemistry, Biomolecular Structure Prediction +12

The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo

Sang Won Hyun, Anguo Liu, Zhenguo Liu et al. · Glycobiology · 2016 · 49 citations · Full text

Medicinal Chemistry, Allergy, Lung Inflammation +12

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold

Hajjaj H.M. Abdu-Allah, Kozo Watanabe, Gladys C. Completo et al. · Bioorganic & Medicinal Chemistry · 2011 · 38 citations · Full text

Nanomedicine, Engineering, Hydrophobic Groups +8