Timothy A. Lewis

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Sovan Sarkar, Ethan Perlstein, Sara Imarisio et al. · Nature Chemical Biology · 2007 · 606 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Crystal Structure of Osmylated C ₆₀ : Confirmation of the Soccer Ball Framework

Joel M. Hawkins, Axel Meyer, Timothy A. Lewis et al. · Science · 1991 · 511 citations

Natural Sciences, Chemistry, Materials Science +17

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

David B. Sykes, Youmna Kfoury, François Mercier et al. · Cell · 2016 · 488 citations · Full text

Medicine, Oncology, Pharmacology +14

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato et al. · Nature · 2016 · 266 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

A. Schuetz, Jinrong Min, Abdellah Allali‐Hassani et al. · Journal of Biological Chemistry · 2008 · 258 citations · Full text

Life Sciences, Molecular Biology, Oncology +10