Timothy A. Lewis

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Sovan Sarkar, Ethan Perlstein, Sara Imarisio et al. · Nature Chemical Biology · 2007 · 603 citations · Full text

Disease Models, Mitophagy, Cell Autophagy +9

Crystal Structure of Osmylated C ₆₀ : Confirmation of the Soccer Ball Framework

Joel M. Hawkins, Axel Meyer, Timothy A. Lewis et al. · Science · 1991 · 510 citations

Materials Science, Inorganic Chemistry, Crystal Structure +13

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

David B. Sykes, Youmna Kfoury, François Mercier et al. · Cell · 2016 · 468 citations · Full text

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato et al. · Nature · 2016 · 261 citations · Full text

Diversity-oriented Synthesis Yields, Medicinal Chemistry, Diversity Oriented Synthesis +7

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

A. Schuetz, Jinrong Min, Abdellah Allali‐Hassani et al. · Journal of Biological Chemistry · 2008 · 254 citations · Full text

Histone Modifications, Human Hdac7, Histone Deacetylases +20