James Spoonamore

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

Michel Weïwer, James Spoonamore, Jingqiang Wei et al. · ACS Medicinal Chemistry Letters · 2012 · 138 citations · Full text

Kinase-selectivity Profiles, Cell Death, Cancer Biology +21

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors

Fei Huang, Nadish Goyal, Katherine Sullivan et al. · Nucleic Acids Research · 2016 · 95 citations · Full text

Genome Instability, Novel Therapy, Single Rad52 Mutations +14

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering

Kristin J. Adolfsen, Isolde Callihan, Catherine Monahan et al. · Nature Communications · 2021 · 91 citations · Full text

A Human Islet Cell Culture System for High-Throughput Screening

Deepika Walpita, Thomas P. Hasaka, James Spoonamore et al. · SLAS DISCOVERY · 2011 · 57 citations · Full text

Discovery of a Novel, Potent, and Specific Family of Factor Xa Inhibitors via Combinatorial Chemistry

James A. Ostrem, Fahad Al‐Obeidi, Pavel Šafář et al. · Biochemistry · 1998 · 47 citations