Lin Tai

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

Brandon J. Aubrey, Gemma L. Kelly, Andrew J. Kueh et al. · Cell Reports · 2015 · 423 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

Lorraine A. O’ Reilly, Lin Tai, Lily Lee et al. · Nature · 2009 · 387 citations · Full text

Life Sciences, Cell Biology, Immunology +14

The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest

Thomas Kaufmann, Lin Tai, Paul G. Ekert et al. · Cell · 2007 · 198 citations

Life Sciences, Cell Biology, Molecular Biology +17

DNA repair processes are critical mediators of p53-dependent tumor suppression

Ana Janic, Liz J. Valente, Matthew J. Wakefield et al. · Nature Medicine · 2018 · 187 citations

Medicine, Cancer Biology, Molecular Biology +16

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in <i>p53</i>

Gemma L. Kelly, Stephanie Grabow, Stefan Glaser et al. · Genes & Development · 2014 · 169 citations · Full text

Life Sciences, Cancer Biology, Oncology +17