XIAP discriminates between type I and type II FAS-induced apoptosis

Philipp J. Jost, Stephanie Grabow, Daniel H.D. Gray, +9

Nature

Signal TransductionAutoimmune DiseaseXiap DiscriminatesMedicineApoptosis +6

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

Lorraine A. O’ Reilly, Lin Tai, Lily Lee, +11

Nature

Proteinlipid InteractionMembrane-bound Fas LigandSignal TransductionBiochemistryNatural Sciences +7

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK

Francine Ke, Hannah Vanyai, Angus D. Cowan, +6

Cell

Developmental BiologyCell DivisionApoptosisCell DeathMorphogenesis +8

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in <i>p53</i>

Gemma L. Kelly, Stephanie Grabow, Stefan Glaser, +16

Genes & Development

Radiation and Local Anti-CD40 Generate an Effective in situ Vaccine in Preclinical Models of Pancreatic Cancer

Sayeda Yasmin‐Karim, Patrick T. Bruck, Michèle Moreau, +6

Frontiers in Immunology

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

Charlotte Viant, Sophie Guia, Robert J. Hennessy, +19

The Journal of Experimental Medicine

Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models

Walid S. Kamoun, Dmitri B. Kirpotin, Zhaohua Huang, +26

Nature Biomedical Engineering

NanomedicineDrug TargetingNanotherapeuticsPolymer-drug ConjugateMedicine +9

Antibody-mediated targeting of TNFR2 activates CD8 ⁺ T cells in mice and promotes antitumor immunity

Eric M. Tam, Ross B. Fulton, James F. Sampson, +32

Science Translational Medicine

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

Bilal N. Sheikh, Stanley Chun-Wei Lee, Farrah El-Saafin, +10

Blood

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Diane Moujalled, Adam Southon, Eiman Saleh, +13

Cell Death and Differentiation