Brandon J. Aubrey

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1K citations

Mcl1 Inhibitor S63845, Systems Biology, Oncology +11

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

Brandon J. Aubrey, Gemma L. Kelly, Andrew J. Kueh et al. · Cell Reports · 2015 · 414 citations · Full text

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell, David J. Leaver, S.J. Hermans et al. · Nature · 2018 · 300 citations · Full text

Cancer Research, Chromatin, Tumour Growth +12

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in <i>p53</i>

Gemma L. Kelly, Stephanie Grabow, Stefan Glaser et al. · Genes & Development · 2014 · 165 citations · Full text

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia M. Moujalled et al. · Blood · 2021 · 128 citations · Full text