Concepedia
Statistics
Publications
9
Citations
1.4K
H-Index
Active since
1990
Affiliations
Trinity College Dublin(Current)
Children's Health Ireland at Crumlin
Monash University
Centenary Institute
Royal College of Surgeons in Ireland
Alexander Hooftman is an author at Trinity College Dublin specializing in medicine, cell biology, and immunology.
Top concepts
MedicineImmunologyCell BiologyCell DeathRna BiologyAutoimmunityInflammationCell SignalingNon-coding RnaGene Expression
Publications per year
1990–2024
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
Alexander Hooftman, Stefano Angiari, Svenja Hester et al. · Cell Metabolism · 2020 · 542 citations · Full text
Inflammation, Anti-inflammatory, Signal Transduction +12
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Marah C. Runtsch, Stefano Angiari, Alexander Hooftman et al. · Cell Metabolism · 2022 · 295 citations
Inflammation, Itaconate Derivatives, Alternative Activation +13
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
Alexander Hooftman, Christian G. Peace, Dylan G. Ryan et al. · Nature · 2023 · 201 citations · Full text
Macrophage Fumarate Hydratase, Rna Biology, Gene Expression +3
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
Mark Hughes, Alexander Hooftman, Stefano Angiari et al. · Cell Reports · 2019 · 86 citations · Full text
Expression of a human homing receptor (CD44) in lymphoid malignancies and related stages of lymphoid development.
E Horst, C J Meijer, T Radaskiewicz et al. · PubMed · 1990 · 84 citations
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