Dajun Yang

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary, Dongguang Qin, Donna McEachern et al. · Proceedings of the National Academy of Sciences · 2008 · 650 citations · Full text

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis

Hai‐Liang Zhang, Bingxin Hu, Zhi‐Ling Li et al. · Nature Cell Biology · 2022 · 504 citations

Redox Signaling, Signal Transduction, Biochemistry +9

Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

Zaneta Nikolovska‐Coleska, Liang Xu, Zengjian Hu et al. · Journal of Medicinal Chemistry · 2004 · 340 citations · Full text

Pharmaceutical Research, Drug Target, Chemoprevention Strategy +19

Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening

Istvan Enyedy, Yan Ling, Kassoum Nacro et al. · Journal of Medicinal Chemistry · 2001 · 312 citations · Full text

Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins

Guoping Wang, Zaneta Nikolovska‐Coleska, Chao‐Yie Yang et al. · Journal of Medicinal Chemistry · 2006 · 293 citations · Full text