Concepedia
Statistics
Publications
6
Citations
268
H-Index
Active since
2018
Affiliations
Xenon Pharmaceuticals (Canada)(Current)
Shanghai Zhangjiang Laboratory
Karen Nelkenbrecher is an author at Xenon Pharmaceuticals (Canada).
Publications per year
2018–2021
Selective NaV1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain
Girish Bankar, Samuel J. Goodchild, Sarah Howard et al. · Cell Reports · 2018 · 75 citations · Full text
Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity
Mohammad‐Reza Ghovanloo, Koushik Choudhury, Tagore Sanketh Bandaru et al. · The Journal of General Physiology · 2021 · 63 citations · Full text
Discovery of Acyl-sulfonamide Na<sub>v</sub>1.7 Inhibitors GDC-0276 and GDC-0310
Brian S. Safina, Steven J. McKerrall, Shaoyi Sun et al. · Journal of Medicinal Chemistry · 2021 · 35 citations · Full text
Identification of Selective Acyl Sulfonamide–Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na <sub>V</sub> ) 1.7 with Potent Analgesic Activity
Shaoyi Sun, Qi Jia, Alla Zenova et al. · Journal of Medicinal Chemistry · 2018 · 34 citations · Full text
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na<sub>V</sub>1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy
Thilo Focken, Kristen Burford, Michael Grimwood et al. · Journal of Medicinal Chemistry · 2019 · 31 citations · Full text
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