Rohan Degaonkar

Reversal of siRNA-mediated gene silencing in vivo

Ivan Zlatev, Adam Castoreno, Christopher R. Brown et al. · Nature Biotechnology · 2018 · 92 citations

Genetics, Antisense Therapy, Small Rna +5

Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5′-exonuclease

Pawan Kumar, Rohan Degaonkar, Dale C. Guenther et al. · Nucleic Acids Research · 2020 · 42 citations · Full text

Chimeric Sirnas, Engineering, Molecular Biology +20

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing

Hartmut Jahns, Rohan Degaonkar, Peter Podbevšek et al. · Nucleic Acids Research · 2021 · 22 citations · Full text

siRNAs containing 2′-fluorinated <i>Northern</i>-methanocarbacyclic (2′-F-NMC) nucleotides: <i>in vitro</i> and <i>in vivo</i> RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs

Masaaki Akabane‐Nakata, Namrata Erande, Pawan Kumar et al. · Nucleic Acids Research · 2021 · 19 citations · Full text