Masaaki Akabane‐Nakata

Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology <i>in vivo</i>

Hartmut Jahns, Nate Taneja, Jennifer L. S. Willoughby et al. · Nucleic Acids Research · 2021 · 75 citations · Full text

Engineering, Rp Isomer, Sp Isomer +17

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics

Shusuke Tomoshige, David A. Dik, Masaaki Akabane‐Nakata et al. · ACS Infectious Diseases · 2018 · 33 citations · Full text

Bioorganic Chemistry, Engineering, Microbial Pathogens +23

siRNAs containing 2′-fluorinated <i>Northern</i>-methanocarbacyclic (2′-F-NMC) nucleotides: <i>in vitro</i> and <i>in vivo</i> RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs

Masaaki Akabane‐Nakata, Namrata Erande, Pawan Kumar et al. · Nucleic Acids Research · 2021 · 19 citations · Full text

Synthesis and Biophysical Characterization of RNAs Containing 2′-Fluorinated <i>Northern</i> Methanocarbacyclic Nucleotides

Masaaki Akabane‐Nakata, Pawan Kumar, Rajat S. Das et al. · Organic Letters · 2019 · 14 citations

Biophysical Characterization, Medicinal Chemistry, Nucleic Acid Chemistry +14

Synthesis of oligonucleotides containing N,N-disubstituted 3-deazacytosine nucleobases by post-elongation modification and their triplex-forming ability with double-stranded DNA

Masaaki Akabane‐Nakata, Satoshi Obika, Yoshiyuki Hari · Organic & Biomolecular Chemistry · 2014 · 12 citations