Jennifer L. S. Willoughby

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Publications

Citations

3.1K

H-Index

Active since

2014

Affiliations

Alnylam Pharmaceuticals (United States)(Current)

Vanderbilt University

Harvard University

University of Toyama

Joslin Diabetes Center

Jennifer L. S. Willoughby is an author at Alnylam Pharmaceuticals (United States) specializing in molecular biology, rna interference, and life sciences.

ORCID

Publications per year

2014–2023

Publications

Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

Jayaprakash K. Nair, Jennifer L. S. Willoughby, Amy Chan et al. · Journal of the American Chemical Society · 2014 · 1.1K citations

Pharmacy, Pharmaceutics, Pharmacology +17

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Samir Softic, Manoj K. Gupta, Guo-Xiao Wang et al. · Journal of Clinical Investigation · 2017 · 344 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates

Jayaprakash K. Nair, Husain Attarwala, Alfica Sehgal et al. · Nucleic Acids Research · 2017 · 270 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Samir Softic, Jesse G. Meyer, Guo-Xiao Wang et al. · Cell Metabolism · 2019 · 231 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +14

siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes

Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair et al. · ACS Chemical Biology · 2015 · 213 citations

Pharmacy, Molecular Biology, Pharmacology +17

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