Concepedia

Jayaprakash K. Nair

JK

Statistics

Publications

16

Citations

3.1K

H-Index

16

Active since

2014

Affiliations

Alnylam Pharmaceuticals (United States)(Current)

Vanderbilt University

Centre for Human Drug Research

Boston University

Massachusetts Institute of Technology

Jayaprakash K. Nair is an author at Alnylam Pharmaceuticals (United States) specializing in medicine, drug discovery, and natural sciences.

ORCID

Top concepts

Publications per year

2014–2023

16

Publications

16

Multivalent <i>N</i>-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

Jayaprakash K. Nair, Jennifer L. S. Willoughby, Amy Chan et al. · Journal of the American Chemical Society · 2014 · 1K citations

An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia

Alfica Sehgal, Scott Barros, Lacramioara Ivanciu et al. · Nature Medicine · 2015 · 290 citations

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Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates

Christopher R. Brown, Swati Gupta, June Qin et al. · Nucleic Acids Research · 2020 · 265 citations · Full text

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Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates

Jayaprakash K. Nair, Husain Attarwala, Alfica Sehgal et al. · Nucleic Acids Research · 2017 · 258 citations · Full text

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 225 citations · Full text

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