Concepedia

Ivan Zlatev

IZ

38

Publications

2.8K

Citations

25

H-Index

2007

Active since

Affiliations

Alnylam Pharmaceuticals (United States)(Current)

Vanderbilt University

Université de Montpellier

Institut des Biomolécules Max Mousseron

Erasmus MC

Ivan Zlatev is an author at Alnylam Pharmaceuticals (United States) specializing in natural sciences, molecular biology, and biochemistry.

Top concepts

Molecular BiologyNatural SciencesBiochemistryMedicineDna ReplicationNucleic Acid BiochemistryChemical BiologyDrug DiscoveryGenome EditingStructural Biology

Publications per year

2007–2024

38

Publications

38

Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides

Naoki Iwamoto, David C. Butler, Nenad Svrzikapa et al. · Nature Biotechnology · 2017 · 358 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +7

Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates

Christopher R. Brown, Swati Gupta, June Qin et al. · Nucleic Acids Research · 2020 · 265 citations · Full text

Sirna Accumulation, Molecular Pharmacology, Medicinal Chemistry +15

Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

Maja M. Janas, Mark K. Schlegel, Carole E. Harbison et al. · Nature Communications · 2018 · 255 citations · Full text

Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 225 citations · Full text

Rnai Therapeutics, Liver Physiology, Gene Delivery +5

Influenza A virus-generated small RNAs regulate the switch from transcription to replication

Jasmine T. Perez, Andrew Varble, Ravi Sachidanandam et al. · Proceedings of the National Academy of Sciences · 2010 · 222 citations

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