Philip C. Wong

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Philip C. Wong, Carlos A. Pardo, David Borchelt et al. · Neuron · 1995 · 1.4K citations

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Huaibin Cai, Yanshu Wang, Diane B. McCarthy et al. · Nature Neuroscience · 2001 · 1K citations

Protein Secretion, Signal Transduction, Molecular Neuroscience +8

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Brian D. Freibaum, Yubing Lu, Nam Chul Kim et al. · Nature · 2015 · 831 citations · Full text

Natural Sciences, Molecular Biology, Dna Replication +6

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

Philip C. Wong, Hui Zheng, Hua Chen et al. · Nature · 1997 · 718 citations

Notch 1, Systems Biology, Cell Biology +2

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

Jonathan P. Ling, Olga Pletniková, Juan C. Troncoso et al. · Science · 2015 · 675 citations

Neurodegenerative Diseases, Systems Biology, Amyotrophic Lateral Sclerosis +13