RAN proteins and RNA foci from antisense transcripts in <i>C9ORF72</i> ALS and frontotemporal dementia

Tao Zu, Yuanjing Liu, Mónica Báñez-Coronel, +11

Proceedings of the National Academy of Sciences

GeneticsAntisense TranscriptsDisease Gene IdentificationSocial SciencesNeurobiology Of Disease +17

<i>S</i> -Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function

Kenny K. K. Chung, Bobby Thomas, Xiaojie Li, +5

Science

Molecular RegulationParkin Regulates UbiquitinationParkin SubstratesProtective FunctionDopamine Neurons +18

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

Jonathan P. Ling, Olga Pletniková, Juan C. Troncoso, +1

Science

Neurodegenerative DiseasesSystems BiologyAmyotrophic Lateral SclerosisBiochemistryNatural Sciences +11

Evidence for brain glucose dysregulation in Alzheimer's disease

Yang An, Vijay R. Varma, Sudhir Varma, +13

Alzheimer s & Dementia

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

Vijay R. Varma, Anup Mammen Oommen, Sudhir Varma, +16

PLoS Medicine

Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

Wenxue Li, Neva West, Emanuela Colla, +8

Proceedings of the National Academy of Sciences

Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease

Tae‐In Kam, Xiaobo Mao, Hyejin Park, +19

Science

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

Jeanne M.M. Tan, Esther Wong, Donald S. Kirkpatrick, +10

Human Molecular Genetics

Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2

David Ramonet, João Paulo Lima Daher, Brian M. Lin, +20

PLoS ONE

MitophagyCellular NeurobiologyCultured Dopaminergic NeuronsSocial SciencesAutophagy +17

Endoplasmic Reticulum Stress Is Important for the Manifestations of α-Synucleinopathy<i>In Vivo</i>

Emanuela Colla, Philippe Coune, Ying Liu, +5

Journal of Neuroscience