Hui Zheng

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

Philip C. Wong, Hui Zheng, Hua Chen et al. · Nature · 1997 · 718 citations

Life Sciences, Cell Biology, Genetics +12

Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Aβ ₄₂ production

Tobias Moehlmann, Edith Winkler, Xuefeng Xia et al. · Proceedings of the National Academy of Sciences · 2002 · 267 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease

Heather A. Born, Ji-Yoen Kim, Ricky R. Savjani et al. · Journal of Neuroscience · 2014 · 191 citations · Full text

Life Sciences, Neurology, Neuroscience +16

Mutant Human Presenilin 1 Protects presenilin 1 Null Mouse against Embryonic Lethality and Elevates Aβ1–42/43 Expression

Su Qian, Ping Jiang, Xiao-Ming Guan et al. · Neuron · 1998 · 168 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Phospholipase D1 corrects impaired βAPP trafficking and neurite outgrowth in familial Alzheimer’s disease-linked presenilin-1 mutant neurons

Dongming Cai, Minghao Zhong, Runsheng Wang et al. · Proceedings of the National Academy of Sciences · 2006 · 105 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17