Yubing Lu

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Brian D. Freibaum, Yubing Lu, Nam Chul Kim et al. · Nature · 2015 · 870 citations

Life Sciences, Genetics, Molecular Biology +9

Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons

Yubing Lu, Tania F. Gendron, Anna Karydas et al. · Neuron · 2016 · 428 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

Hélène Tran, Sandra Almeida, Jill E. Moore et al. · Neuron · 2015 · 196 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

Zhijun Zhang, Sandra Almeida, Yubing Lu et al. · PLoS ONE · 2013 · 139 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions

Dejun Yang, Abbas Abdallah, Zhaodong Li et al. · Acta Neuropathologica · 2015 · 137 citations · Full text

Life Sciences, Genetics, Neuroscience +17