Stuart C. Chaffee

Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

Brian L. Hodous, Stephanie Geuns-Meyer, Paul E. Hughes et al. · Journal of Medicinal Chemistry · 2007 · 91 citations · Full text

Molecular Biology, Pharmacotherapy, Chemical Biology +21

Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors

Brian L. Hodous, Stephanie Geuns-Meyer, Paul E. Hughes et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 33 citations · Full text

Medicinal Chemistry, Derivative (Chemistry), Engineering +10

Alkynylpyrimidine Amide Derivatives as Potent, Selective, and Orally Active Inhibitors of Tie-2 Kinase

Victor J. Cee, Brian K. Albrecht, Stephanie Geuns-Meyer et al. · Journal of Medicinal Chemistry · 2007 · 29 citations · Full text

Efficient construction of the securine A carbon skeleton

Peter Korakas, Stuart C. Chaffee, J. Brad Shotwell et al. · Proceedings of the National Academy of Sciences · 2004 · 27 citations · Full text

Materials Science, Intriguing Alkaloid, Carbonization +14

Structure-Guided Design of Aminopyrimidine Amides as Potent, Selective Inhibitors of Lymphocyte Specific Kinase: Synthesis, Structure–Activity Relationships, and Inhibition of in Vivo T Cell Activation

Erin F. DiMauro, John Newcomb, Joseph J. Nunes et al. · Journal of Medicinal Chemistry · 2008 · 22 citations · Full text