Joseph J. Nunes

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Medicine, Medicinal Chemistry, Molecular Biology +14

Dramatic rate accelerations of Diels-Alder reactions in 5 M lithium perchlorate-diethyl ether: the cantharidin problem reexamined

Paul A. Grieco, Joseph J. Nunes, Micheal D. Gaul · Journal of the American Chemical Society · 1990 · 325 citations

Natural Sciences, Chemistry, Chemical Kinetics +5

Discovery of Imidazo[1,2- <i>b</i> ]thiazole Derivatives as Novel SIRT1 Activators

Chi B. Vu, Jean E. Bemis, Jeremy S. Disch et al. · Journal of Medicinal Chemistry · 2009 · 120 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators

Jean E. Bemis, Chi B. Vu, Roger L. Xie et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 90 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Stereocontrolled total synthesis of (.+-.)-quinocarcin

Toru. Fukuyama, Joseph J. Nunes · Journal of the American Chemical Society · 1988 · 71 citations

Natural Sciences, Chemistry, Bioisosterism +6