Emilio Álvarez-Ruíz

Fueling Open‐Source Drug Discovery: 177 Small‐Molecule Leads against Tuberculosis

Lluís Ballell, Robert H. Bates, Rob J. Young et al. · ChemMedChem · 2013 · 310 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

María José Rebollo-López, Joël Lelièvre, Daniel Álvarez-Gómez et al. · PLoS ONE · 2015 · 45 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold

Stane Pajk, Matej Živec, Roman Šink et al. · European Journal of Medicinal Chemistry · 2016 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Lead Discovery for Microsomal Prostaglandin E Synthase Using a Combination of High-Throughput Fluorescent-Based Assays and RapidFire Mass Spectrometry

Melanie Leveridge, Ana I. Bardera, William A. LaMarr et al. · SLAS DISCOVERY · 2012 · 23 citations · Full text

Pharmacy, Biochemistry, Pharmacology +15