Concepedia

Heather P. O’Keefe

HP

Statistics

Publications

8

Citations

1.2K

H-Index

8

Active since

2006

Affiliations

GlaxoSmithKline (United States)(Current)

GlaxoSmithKline (United Kingdom)

Research Triangle Park Foundation

GlaxoSmithKline (Spain)

Heather P. O’Keefe is an author at GlaxoSmithKline (United States) specializing in drug discovery, medicinal chemistry, and pharmacy.

Publications per year

2006–2022

8

Publications

8

Design, synthesis and selection of DNA-encoded small-molecule libraries

Matthew Clark, Raksha Acharya, Christopher C. Arico-Muendel et al. · Nature Chemical Biology · 2009 · 691 citations · Full text

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Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

Hongfeng Deng, Heather P. O’Keefe, Christopher P. Davie et al. · Journal of Medicinal Chemistry · 2012 · 149 citations · Full text

, , +14

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

, , +17

Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT)

Yun Ding, Heather P. O’Keefe, Jennifer L. DeLorey et al. · ACS Medicinal Chemistry Letters · 2015 · 77 citations · Full text

, , +16

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Carl A. Machutta, Christopher S. Kollmann, Kenneth Lind et al. · Nature Communications · 2017 · 74 citations · Full text

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