X-ray Crystal Structure of Human Dopamine Sulfotransferase, SULT1A3

Rana Dajani, Anne Cleasby, Margarete Neu, +8

Journal of Biological Chemistry

X-ray solution scattering reveals conformational changes upon iron uptake in lactoferrin, serum and ovo-transferrins

J. Günter Grossmann, Margarete Neu, E. Pantos, +7

Journal of Molecular Biology

Reveals Conformational ChangesBiochemistryIron MetabolismX-ray SolutionBioanalysis +3

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu, +26

Journal of Medicinal Chemistry

Bioorganic ChemistryHit IdentificationPharmaceutical ChemistryDrug ResistanceMedicinal Chemistry +20

The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 Å, respectively

David R. Hall, Jonathan M. Hadden, Gordon A. Leonard, +4

Acta Crystallographica Section D Biological Crystallography

Pharmaceutical ScienceProtein AssemblyRabbit Serum TransferrinsSpace Group C2Protein Folding +16

Identification of KasA as the cellular target of an anti-tubercular scaffold

Katherine A. Abrahams, Chun-wa Chung, Sonja Ghidelli‐Disse, +27

Nature Communications

N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3

Richard Angell, Francis Atkinson, Murray J. B. Brown, +15

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineRational Drug DesignDrug DevelopmentPharmacology +2

Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors

J. Hamblin, Tony D. Angell, Stuart P. Ballantine, +13

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryNovel Structural ClassBiochemistryMedicineRational Drug Design +4

X-ray scattering using synchrotron radiation shows nitrite reductase from Achromobacter xylosoxidans to be a trimer in solution

J. Guenter Grossmann, Z. H. L. Abraham, Elinor T. Adman, +4

Biochemistry

Image correction for atomic force microscopy images with functionalized tips

Margarete Neu, Nikolaj Moll, G. Meyer, +1

Physical Review B

Atomic Force MicroscopyEngineeringElectron MicroscopyCo-functionalized TipsMicrofabrication +13

Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode

Michael Kranz, Michael Wall, Brian Evans, +9

Bioorganic & Medicinal Chemistry

Molecular RecognitionMedicinal ChemistryDrug TargetNatural SciencesMedicine +8