Christopher P. Davie

Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

Hongfeng Deng, Heather P. O’Keefe, Christopher P. Davie et al. · Journal of Medicinal Chemistry · 2012 · 147 citations · Full text

Drug Target, Complex Mixtures, Molecular Biology +21

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Bioorganic Chemistry, Hit Identification, Pharmaceutical Chemistry +22

Design and Application of a DNA-Encoded Macrocyclic Peptide Library

Zhengrong Zhu, Alex Shaginian, LaShadric C. Grady et al. · ACS Chemical Biology · 2017 · 103 citations

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

Hongfeng Deng, Jingye Zhou, Flora S. Sundersingh et al. · ACS Medicinal Chemistry Letters · 2015 · 82 citations · Full text

Combinatorial Chemistry, Drug Target, Bioorganic Chemistry +24

Ruthenium Promoted On-DNA Ring-Closing Metathesis and Cross-Metathesis

Xiaojie Lu, Lijun Fan, Christopher B. Phelps et al. · Bioconjugate Chemistry · 2017 · 80 citations