Melanie Leveridge

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 932 citations · Full text

Inflammation, Cytokine, Inflammatory Disease +12

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Natalie H. Theodoulou, Paul Bamborough, Andrew J. Bannister et al. · Journal of Medicinal Chemistry · 2015 · 229 citations · Full text

Chemical Biology, Chromatin, Molecular Characterization +14

The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond

Carl Haslam, John Hellicar, Adrian J. Dunn et al. · SLAS DISCOVERY · 2015 · 136 citations · Full text

Enabling Lead Discovery for Histone Lysine Demethylases by High-Throughput RapidFire Mass Spectrometry

Sue Hutchinson, Melanie Leveridge, Michelle L. Heathcote et al. · SLAS DISCOVERY · 2011 · 99 citations · Full text

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Derivatives

Susan M. Westaway, Alex Preston, Michael D. Barker et al. · Journal of Medicinal Chemistry · 2016 · 67 citations · Full text

Drug Target, Molecular Biology, Kdm5 Families +18