Daniel Álvarez-Gómez

Fueling Open‐Source Drug Discovery: 177 Small‐Molecule Leads against Tuberculosis

Lluís Ballell, Robert H. Bates, Rob J. Young et al. · ChemMedChem · 2013 · 308 citations · Full text

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Bioorganic Chemistry, Hit Identification, Pharmaceutical Chemistry +22

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor

María Martínez-Hoyos, Esther Pérez‐Herrán, Gülçin Gülten et al. · EBioMedicine · 2016 · 81 citations · Full text

Design, Synthesis, and Evaluation of New Thiadiazole-Based Direct Inhibitors of Enoyl Acyl Carrier Protein Reductase (InhA) for the Treatment of Tuberculosis

Roman Šink, Izidor Sosič, Matej Živec et al. · Journal of Medicinal Chemistry · 2014 · 76 citations

Combinatorial Chemistry, Competitive Inha Inhibitors, Bioorganic Chemistry +16

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

María José Rebollo-López, Joël Lelièvre, Daniel Álvarez-Gómez et al. · PLoS ONE · 2015 · 45 citations · Full text

Drug Target, Structural Similarity, Pharmaceutical Chemistry +19