Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +14

Cell Reports

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

D. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, +19

Nature

Pyrimidine InhibitorsMedicineAntiviral Drug DevelopmentPharmacotherapyPharmacology +2

Pharmacological activation of STING blocks SARS-CoV-2 infection

Minghua Li, Max Ferretti, Baoling Ying, +17

Science Immunology

Innate Immune PathwaysInnate Immune SystemImmunologyViral PathogenesisRespiratory Epithelial Cells +14

SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

Christine Vazquez, Sydnie Swanson, Seble G. Negatu, +5

PLoS ONE

Distinct MechanismsInflammatory Lung DiseaseLung InflammationViral PathogenesisImmunology +16

Identification of antiviral roles for the exon–junction complex and nonsense-mediated decay in flaviviral infection

Minghua Li, Jeffrey R. Johnson, Billy Truong, +10

Nature Microbiology

Molecular VirologyPathogenesisFlaviviral InfectionMolecular BiologyVirology +7

Protective Effect of TEMPOL Derivatives against Light-Induced Retinal Damage in Rats

Masaki Tanito, Feng Li, Michael H. Elliott, +2

Investigative Ophthalmology & Visual Science

Viral-induced alternative splicing of host genes promotes influenza replication

Matthew G. Thompson, Mark Dittmar, Michael J. Mallory, +5

eLife

Viral ReplicationSystems BiologyNuclear SpecklesPathogenesisRna Splicing +11

Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +7

Lung CellsDrug RepositioningScreens Reveal FdaMedicineImmunology +11

Drug Repurposing Screens Reveal FDA Approved Drugs Active Against SARS-CoV-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +6

SSRN Electronic Journal

L-NAME protects against acute light damage in albino rats, but not against retinal degeneration in P23H and S334ter transgenic rats

Ildikó Káldi, Mark Dittmar, Paula Pierce, +1

Experimental Eye Research

Ocular DiseaseRetinaPhotoreceptor CellOphthalmologyExperimental Ophthalmology +9