Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +14

Cell Reports

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

D. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, +19

Nature

Pyrimidine InhibitorsMedicineAntiviral Drug DevelopmentPharmacotherapyPharmacology +2

Pharmacological activation of STING blocks SARS-CoV-2 infection

Minghua Li, Max Ferretti, Baoling Ying, +17

Science Immunology

Innate Immune PathwaysInnate Immune SystemImmunologyViral PathogenesisRespiratory Epithelial Cells +14

Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer

Yong Gu Lee, Puneeth Guruprasad, Guido Ghilardi, +26

Cancer Discovery

Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +7

Lung CellsDrug RepositioningScreens Reveal FdaMedicineImmunology +11

Drug Repurposing Screens Reveal FDA Approved Drugs Active Against SARS-CoV-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +6

SSRN Electronic Journal

High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy

Emanuele Loro, Kasturi Sengupta, Sasha Bogdanovich, +4

Scientific Reports

Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress

R. Jason Kirby, Daniela Divlianska, Kanupriya Whig, +11

Journal of Pharmacology and Experimental Therapeutics

Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators

S. Jeson Sangaralingham, Kanupriya Whig, Satyamaheshwar Peddibhotla, +11

Proceedings of the National Academy of Sciences

The lncRNA ALPHA specifically targets chikungunya virus to control infection

Megha Basavappa, Max Ferretti, Mark Dittmar, +10

Molecular Cell

Viral ReplicationMolecular VirologyGeneticsPathogenesisVirology +5