SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

D. Schultz, Kasirajan Ayyanathan, Dmitri Negorev, +2

Genes & Development

KAP-1 Corepressor Protein Interacts and Colocalizes with Heterochromatic and Euchromatic HP1 Proteins: a Potential Role for Krüppel-Associated Box–Zinc Finger Proteins in Heterochromatin-Mediated Gene Silencing

Robert F. Ryan, D. Schultz, Kasirajan Ayyanathan, +4

Molecular and Cellular Biology

Molecular RegulationGeneticsMolecular BiologyEpigeneticsTranscriptional Regulation +19

Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation

Kasirajan Ayyanathan, Mark S. Lechner, Peter A. Bell, +6

Genes & Development

Histone ModificationsEpigenetic ChangeGeneticsStable GeneEpigenetics +21

Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2

Mark Dittmar, Jae Seung Lee, Kanupriya Whig, +14

Cell Reports

The LIM Protein AJUBA Recruits Protein Arginine Methyltransferase 5 To Mediate SNAIL-Dependent Transcriptional Repression

Zhaoyuan Hou, Hongzhuang Peng, Kasirajan Ayyanathan, +4

Molecular and Cellular Biology

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

D. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, +19

Nature

Pyrimidine InhibitorsMedicineAntiviral Drug DevelopmentPharmacotherapyPharmacology +2

Cloning and Chromosomal Localization of the Human P2Y1 Purinoceptor

Kasirajan Ayyanathan, Tania E. Webbs, Arbansjit K. Sandhu, +3

Biochemical and Biophysical Research Communications

BiologyChromatinMolecular PhysiologyGeneticsGenomic Mechanism +4

Molecular Cloning of a Novel P2 Purinoceptor from Human Erythroleukemia Cells

G. K. Mohammed Akbar, Venkat Dasari, Tania E. Webb, +8

Journal of Biological Chemistry

An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors

Andrew Chang, Yuanjie Liu, Kasirajan Ayyanathan, +9

Genes & Development

Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage

Kasirajan Ayyanathan, Shailaja Kesaraju, Ken Dawson‐Scully, +1

PLoS ONE

Chemoprevention StrategyBiochemistryMitochondrial FunctionMitochondrial DysfunctionMedicine +13