SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

Peter Halfmann, Shun Iida, Kiyoko Iwatsuki‐Horimoto, +80

Nature

The antigenic anatomy of SARS-CoV-2 receptor binding domain

Wanwisa Dejnirattisai, Daming Zhou, Helen M. Ginn, +50

Cell

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

Rita E. Chen, Emma S. Winkler, James Brett Case, +31

Nature

Sars-cov-2 Variant StrainsVaccine TargetImmunologyMedicineCovid-19

Pharmacological activation of STING blocks SARS-CoV-2 infection

Minghua Li, Max Ferretti, Baoling Ying, +17

Science Immunology

Innate Immune PathwaysInnate Immune SystemImmunologyViral PathogenesisRespiratory Epithelial Cells +14

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice

Suzanne M. Scheaffer, Diana Lee, Bradley Whitener, +18

Nature Medicine

VaccinationVaccine DevelopmentVaccine TargetImmunologyVirology +5

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

Wafaa B. Alsoussi, Sameer Kumar Malladi, Julian Q. Zhou, +30

Nature

B Cell ResponseAdaptive Immune SystemHumoral ResponseImmunologyImmunologic Mechanism +5

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

Ahmed O. Hassan, Swathi Shrihari, Matthew J. Gorman, +16

Cell Reports

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

Andrew C. Hunt, James Brett Case, Young‐Jun Park, +44

Science Translational Medicine

New VariantsViral DiagnosticsViral PathogenesisImmunologyMolecular Biology +15

Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice

Baoling Ying, Suzanne M. Scheaffer, Bradley Whitener, +21

Cell

VaccinationVaccine DevelopmentVaccine TargetPathogenesisImmunology +6

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

Michael Diamond, Peter Halfmann, Tadashi Maemura, +62