Yasuhiko Komatsu

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Ryohei Furumai, Akihisa Matsuyama, Nobuyuki Kobashi et al. · PubMed · 2002 · 744 citations

Reductive Stress, Disulfide Bond, Biochemistry +15

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

Ryohei Furumai, Yasuhiko Komatsu, Norikazu Nishino et al. · Proceedings of the National Academy of Sciences · 2000 · 410 citations · Full text

Hdac6 Inhibition, Bioorganic Chemistry, Aldo-keto Reductase +20

Protein lysine methyltransferase G9a acts on non-histone targets

Philipp Rathert, Arunkumar Dhayalan, Marie Murakami et al. · Nature Chemical Biology · 2008 · 333 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +9

Survival Rate of Microbes after Freeze-Drying and Long-Term Storage

Yukie Miyamoto‐Shinohara, Takashi Imaizumi, Junji Sukenobe et al. · Cryobiology · 2000 · 154 citations

Microbial Inactivation, Shelf Life, Food Spoilage +6

Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.

Yasuhiko Komatsu, Kin‐ya Tomizaki, Makiko Tsukamoto et al. · PubMed · 2001 · 146 citations

Bioorganic Chemistry, Antitumor Activity, Chemoprevention Strategy +18