Norikazu Nishino

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Ryohei Furumai, Akihisa Matsuyama, Nobuyuki Kobashi et al. · PubMed · 2002 · 744 citations

Reductive Stress, Disulfide Bond, Biochemistry +15

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

Ryohei Furumai, Yasuhiko Komatsu, Norikazu Nishino et al. · Proceedings of the National Academy of Sciences · 2000 · 410 citations · Full text

Hdac6 Inhibition, Bioorganic Chemistry, Aldo-keto Reductase +20

Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation

Eunjoo Jeon, Kwang-Youl Lee, Nam-Sook Choi et al. · Journal of Biological Chemistry · 2006 · 340 citations · Full text

Mechanobiology, Sclerostin, Developmental Biology +12

Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G Inhibition with peptide chloromethyl ketones

James C. Powers, B. Frank Gupton, A. Dale Harley et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1977 · 222 citations

Biochemistry, Natural Sciences, Physiology +6

Design of potent reversible inhibitors for thermolysin. Peptides containing zinc coordinating ligands and their use in affinity chromatography

Norikazu Nishino, James C. Powers · Biochemistry · 1979 · 155 citations

Biochemistry 1979, Molecular Pharmacology, Medicinal Chemistry +14