The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation

Arunkumar Dhayalan, Arumugam Rajavelu, Philipp Rathert, +4

Journal of Biological Chemistry

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Philipp Rathert, Mareike Roth, Tobias Neumann, +20

Nature

Transcriptional RegulationLineage PlasticityDevelopmental BiologyGeneticsGenomic Mechanism +6

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

Yingying Zhang, Renata Z. Jurkowska, Szabolcs Soeroes, +8

Nucleic Acids Research

Protein lysine methyltransferase G9a acts on non-histone targets

Philipp Rathert, Arunkumar Dhayalan, Marie Murakami, +7

Nature Chemical Biology

Histone ModificationsChromatinTranscriptional RegulationChromatin RemodelingNatural Sciences +7

The histone chaperone CAF-1 safeguards somatic cell identity

Sihem Cheloufi, Ulrich Elling, Barbara Hopfgartner, +33

Nature

ChromatinChromatin RemodelingEpigenomicsMedicineCell Biology +1

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

Arunkumar Dhayalan, Srikanth Kudithipudi, Philipp Rathert, +1

Chemistry & Biology

BioinformaticsStructural BioinformaticsSpecificity Analysis-based IdentificationGeneticsDna Methylation +11

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

Ina Bock, Arunkumar Dhayalan, Srikanth Kudithipudi, +3

Epigenetics

Epigenetic ChangePeptide EngineeringMolecular BiologyEpigeneticsPeptide Arrays +20

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

Sara Sdelci, André F. Rendeiro, Philipp Rathert, +34

Nature Genetics

Transcriptional RegulationMolecular RegulationNatural SciencesGeneticsMolecular Biology +5

Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

Cristiana Lungu, Sabine Pinter, Julian Broche, +2

Nature Communications

Histone ModificationsEpigenetic ChangeGeneticsLive Cell DetectionMolecular Biology +21

Analysis of the Substrate Specificity of the Dim-5 Histone Lysine Methyltransferase Using Peptide Arrays

Philipp Rathert, Xing Zhang, Christian Freund, +2

Chemistry & Biology

ChromatinBiochemistryNatural SciencesMedicineSubstrate Specificity +10