Seventy-five genetic loci influencing the human red blood cell

Pim van der Harst, Weihua Zhang, Irene Mateo Leach, +188

Nature

Seventy-five Genetic LociGeneticsHematologyBlood CellHeme Homeostasis

The histone chaperone CAF-1 safeguards somatic cell identity

Sihem Cheloufi, Ulrich Elling, Barbara Hopfgartner, +33

Nature

ChromatinChromatin RemodelingEpigenomicsMedicineCell Biology +1

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

Ulrich Elling, Jasmin Taubenschmid, Gerald Wirnsberger, +13

Cell stem cell

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyReverse GeneticsCell Specialization +7

A Global In Vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, +32

Cell

Systems BiologyDevelopmental BiologyMolecular PhysiologyGeneticsConserved Regulator +8

Single-cell brain organoid screening identifies developmental defects in autism

Chong Li, Jonas Simon Fleck, Catarina Martins‐Costa, +12

Nature

Murine inner cell mass-derived lineages depend on Sall4 function

Ulrich Elling, Christian Klasen, Tobias Eisenberger, +2

Proceedings of the National Academy of Sciences

A human tissue screen identifies a regulator of ER secretion as a brain-size determinant

Christopher Esk, Dominik Lindenhofer, Simon Haendeler, +8

Science

Comparative glycoproteomics of stem cells identifies new players in ricin toxicity

Johannes Stadlmann, Jasmin Taubenschmid, D. Wénzel, +7

Nature

GlycoproteomicsReductive StressGlycosylationBiomedical ResearchMedicine +12

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

Georg Michlits, Julian Jude, Matthias Hinterndorfer, +11

Nature Methods

BiologyAllelic VariantGeneticsLong Non-coding RnaLoss-of-function Alleles +6

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

Kaan Boztuǧ, Päivi M. Järvinen, Elisabeth Salzer, +32

Nature Genetics

Jagn1 DeficiencyHematological MalignancyBone Marrow FailureAutoimmune DiseaseHematology +8