Organoid single-cell genomic atlas uncovers human-specific features of brain development

Sabina Kanton, Michael James Boyle, Zhisong He, +14

Nature

Human CellDevelopmental BiologyBrain DevelopmentMedicineSingle Cell Sequencing +8

Inferring and perturbing cell fate regulomes in human brain organoids

Jonas Simon Fleck, Sophie Jansen, Damian Wollny, +8

Nature

Single-cell brain organoid screening identifies developmental defects in autism

Chong Li, Jonas Simon Fleck, Catarina Martins‐Costa, +12

Nature

Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

Jonas Simon Fleck, Fátima Sanchís-Calleja, Zhisong He, +4

Cell stem cell

BioinformaticsFunctional GenomicsEngineeringSingle Cell SequencingMedicine +11

Multimodal spatiotemporal phenotyping of human retinal organoid development

Philipp Wahle, Giovanna Brancati, Christoph Harmel, +24

Nature Biotechnology

Single-cell analyses of axolotl telencephalon organization, neurogenesis, and regeneration

Katharina Lust, Ashley Maynard, Tomás Gomes, +4

Science

NeurogenomicsBrain DevelopmentSynaptic TransmissionAxolotl Telencephalon OrganizationCerebral Organoid +22

An integrated transcriptomic cell atlas of human neural organoids

Zhisong He, Leander Dony, Jonas Simon Fleck, +9

Nature

Accurate <i>de novo</i> identification of biosynthetic gene clusters with GECCO

Laura M. Carroll, Martin Larralde, Jonas Simon Fleck, +4

Inferring and perturbing cell fate regulomes in human cerebral organoids

Jonas Simon Fleck, Sophie Jansen, Damian Wollny, +6

EngineeringBrain DevelopmentCerebral OrganoidCellular PhysiologyEpendyma +20

What is a cell type?

Jonas Simon Fleck, J. Gray Camp, Barbara Treutlein

Science

Human Model SystemsEngineeringCytoskeletonNext StepCell Specialization +15