Concepedia

Protein lysine methyltransferase G9a acts on non-histone targets

Philipp Rathert, Arunkumar Dhayalan, Marie Murakami, Xing Zhang, Raluca Tamas, Renata Z. Jurkowska, Yasuhiko Komatsu, Yoichi Shinkai, Xiaodong Cheng, Albert Jeltsch

Nature Chemical Biology · 2008 · 336 citations · 15 references

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15

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Stephen Rea, Frank Eisenhaber, Dónal O’Carroll et al. · Nature · 2000 · 2.8K citations

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G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

Makoto Tachibana, Kenji Sugimoto, Masami Nozaki et al. · Genes & Development · 2002 · 1.2K citations · Full text

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Structure of HP1 Chromodomain Bound to a Lysine 9-Methylated Histone H3 Tail

Steven Jacobs, Sepideh Khorasanizadeh · Science · 2002 · 837 citations

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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

Makoto Tachibana, Jun Ueda, Mikiko Fukuda et al. · Genes & Development · 2005 · 830 citations · Full text

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SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

Makoto Tachibana, Kenji Sugimoto, Tatsunobu Fukushima et al. · Journal of Biological Chemistry · 2001 · 775 citations · Full text

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