Concepedia

Amy Sambrone

AS

Statistics

Publications

15

Citations

1.2K

H-Index

13

Active since

2012

Affiliations

WuXi AppTec (China)(Current)

Charles River Laboratories (United Kingdom)

Gene Therapy Laboratory

Shanghai Zhangjiang Laboratory

Amy Sambrone is an author at WuXi AppTec (China) specializing in pharmacy, pharmacology, and drug discovery.

Publications per year

2012–2021

15

Publications

15

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 320 citations

Medicine, Oncology, Pharmacology +17

GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer

Jun Liang, Robert A. Blake, Jae H. Chang et al. · Journal of Medicinal Chemistry · 2021 · 135 citations · Full text

Medicine, Oncology, Pharmacology +15

Lead identification of novel and selective TYK2 inhibitors

Jun Liang, Vickie Tsui, Anne van Abbema et al. · European Journal of Medicinal Chemistry · 2013 · 123 citations · Full text

Pharmacy, Chemical Biology, Chemistry +14

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

Vernon T. Phan, Xiumin Wu, Jason Cheng et al. · Proceedings of the National Academy of Sciences · 2013 · 115 citations · Full text

Medicine, Cell Biology, Oncology +17

Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1

Yu Zhong, Paula Katavolos, Tien‐Trung Nguyen et al. · Toxicologic Pathology · 2015 · 102 citations · Full text

Medicine, Oncology, Pharmacology +13

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