Jae H. Chang

GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer

Jun Liang, Robert A. Blake, Jae H. Chang et al. · Journal of Medicinal Chemistry · 2021 · 130 citations · Full text

Blood–Brain Barrier Penetrating Biologic TNF-α Inhibitor for Alzheimer’s Disease

Rudy Chang, Jillian Knox, Jae H. Chang et al. · Molecular Pharmaceutics · 2017 · 124 citations

Helminth-induced alterations of the gut microbiota exacerbate bacterial colitis

Chien‐Wen Su, Long Su, Y Li et al. · Mucosal Immunology · 2017 · 110 citations · Full text

Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors

Shannon D. Shields, Lunbin Deng, Rebecca M. Reese et al. · Journal of Neuroscience · 2018 · 84 citations · Full text

Rosuvastatin Pharmacokinetics in Asian and White Subjects Wild Type for Both OATP1B1 and BCRP Under Control and Inhibited Conditions

Hsin-Fang Wu, Nadya Hristeva, Jae H. Chang et al. · Journal of Pharmaceutical Sciences · 2017 · 78 citations · Full text