Jae H. Chang

GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer

Jun Liang, Robert A. Blake, Jae H. Chang et al. · Journal of Medicinal Chemistry · 2021 · 135 citations · Full text

Medicine, Oncology, Pharmacology +15

Blood–Brain Barrier Penetrating Biologic TNF-α Inhibitor for Alzheimer’s Disease

Rudy Chang, Jillian Knox, Jae H. Chang et al. · Molecular Pharmaceutics · 2017 · 127 citations

Life Sciences, Neuroscience, Pharmacology +17

Helminth-induced alterations of the gut microbiota exacerbate bacterial colitis

Chien‐Wen Su, Long Su, Y Li et al. · Mucosal Immunology · 2017 · 115 citations · Full text

Veterinary Medicine, Immunology, Microbiology +13

Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors

Shannon D. Shields, Lunbin Deng, Rebecca M. Reese et al. · Journal of Neuroscience · 2018 · 92 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Rosuvastatin Pharmacokinetics in Asian and White Subjects Wild Type for Both OATP1B1 and BCRP Under Control and Inhibited Conditions

Hsin-Fang Wu, Nadya Hristeva, Jae H. Chang et al. · Journal of Pharmaceutical Sciences · 2017 · 79 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15