Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells

Farbod Shojaei, Xiumin Wu, Ajay K. Malik, +6

Nature Biotechnology

Hematological MalignancyOncologyMedicineCd11b+gr1+ Myeloid CellsMyeloid Neoplasia +8

Therapeutic antibody targeting of individual Notch receptors

Yan Wu, Carol Cain-Hom, Lisa Choy, +21

Nature

ImmunologyReceptor (Biochemistry)ImmunochemistryAntibody EngineeringImmunotherapy +3

Bv8 regulates myeloid-cell-dependent tumour angiogenesis

Farbod Shojaei, Xiumin Wu, Cuiling Zhong, +13

Nature

Myeloid-cell-dependent Tumour AngiogenesisMalignant Blood DisorderMyelopoiesisMedicineCell Biology +2

PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment

Yongping Crawford, Ian Kasman, Lanlan Yu, +5

Cancer Cell

Tumors RefractoryAngiogenesisPathologyFibroblast Growth FactorVascular Biology +9

Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, +8

The EMBO Journal

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

Farbod Shojaei, Xiumin Wu, Xueping Qu, +5

Proceedings of the National Academy of Sciences

ImmunologyG-csf ExpressionImmunotherapyTumor BiologyAngiogenesis +15

An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

Alicia S. Chung, Xiumin Wu, Guanglei Zhuang, +9

Nature Medicine

InflammationCytokineCancer ImmunosurveillanceMedicineImmunology +6

Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF

Wei‐Ching Liang, Xiumin Wu, Franklin Peale, +8

Journal of Biological Chemistry

Interaction between Bevacizumab and Murine VEGF-A: A Reassessment

Lanlan Yu, Xiumin Wu, Zhiyong Cheng, +6

Investigative Ophthalmology & Visual Science

Quantifying Antivascular Effects of Monoclonal Antibodies to Vascular Endothelial Growth Factor: Insights from Imaging

James P.B. O’Connor, Richard A.D. Carano, Andrew R. Clamp, +26

Clinical Cancer Research