Michiko Tawada

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

Kazuhide Nakayama, Magdalena M. Szewczyk, Carlo dela Seña et al. · Oncotarget · 2018 · 135 citations · Full text

Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins

Yuta Tanaka, Katsuji Aikawa, Goushi Nishida et al. · Journal of Medicinal Chemistry · 2013 · 108 citations · Full text

Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors

Shigemitsu Matsumoto, Naoki Miyamoto, Takaharu Hirayama et al. · Bioorganic & Medicinal Chemistry · 2013 · 54 citations · Full text

Combinatorial Chemistry, Vegfr2 Kinase Inhibitors, Medicinal Chemistry +11

Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: Discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics

Yuya Oguro, Douglas R. Cary, Naoki Miyamoto et al. · Bioorganic & Medicinal Chemistry · 2013 · 50 citations · Full text

Medicinal Chemistry, Medicine, Drug Discovery +8

Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554

Yoshihiro Banno, Yasufumi Miyamoto, Mitsuru Sasaki et al. · Bioorganic & Medicinal Chemistry · 2011 · 42 citations · Full text

Medicinal Chemistry, Unique Interaction, Bioorganic Chemistry +10