Publication | Open Access

Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554

Medicinal ChemistryUnique InteractionBioorganic ChemistryBiochemistryNatural SciencesMedicineRational Drug DesignPeptide SynthesisNew ClassNon-peptide LigandPharmacologyPharmaceutical ChemistryDrug Discovery