Timothy J. Kieffer

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

Alireza Rezania, Jennifer E. Bruin, Payal Arora et al. · Nature Biotechnology · 2014 · 1.6K citations

Life Sciences, Cell Biology, Endocrinology +14

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

Timothy J. Kieffer, Christopher H.S. McIntosh, Raymond A. Pederson · Endocrinology · 1995 · 1.1K citations

Life Sciences, Biochemistry, Endocrinology +17

Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women

Karen L. Teff, Sharon S. Elliott, Matthias H. Tschöp et al. · The Journal of Clinical Endocrinology & Metabolism · 2004 · 746 citations · Full text

Life Sciences, Nutritional Sciences, Physiology +16

Maturation of Human Embryonic Stem Cell–Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

Alireza Rezania, Jennifer E. Bruin, Michael Riedel et al. · Diabetes · 2012 · 599 citations · Full text

Life Sciences, Biotechnology, Cell Biology +17

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.

Doris A. Stoffers, Timothy J. Kieffer, Mehboob A. Hussain et al. · Diabetes · 2000 · 579 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17