Jennifer E. Bruin

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

Alireza Rezania, Jennifer E. Bruin, Payal Arora et al. · Nature Biotechnology · 2014 · 1.6K citations

Regenerative Medicine, Induced Pluripotent Stem Cell, Developmental Biology +10

Maturation of Human Embryonic Stem Cell–Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

Alireza Rezania, Jennifer E. Bruin, Michael Riedel et al. · Diabetes · 2012 · 590 citations · Full text

Adult Stem Cell, Stem Cell Biology, Insulin Signaling +17

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo

Alireza Rezania, Jennifer E. Bruin, Jean Xu et al. · Stem Cells · 2013 · 260 citations

Adult Stem Cell, Immunology, Pancreas Transplantation +21

Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice

Jennifer E. Bruin, Alireza Rezania, Jean Xu et al. · Diabetologia · 2013 · 208 citations

Tissue Engineering, Regenerative Medicine, Islet Transplantation +14

Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells

Jennifer E. Bruin, Süheda Erener, Javier Vela et al. · Stem Cell Research · 2013 · 194 citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +13