Maureen M. Hattersley

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Chaoyang Sun, Yong Fang, Jian Chen et al. · Cancer Cell · 2018 · 302 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies

Garrett W. Rhyasen, Maureen M. Hattersley, Yi Yao et al. · Molecular Cancer Therapeutics · 2016 · 157 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)

Edward J. Hennessy, Ammar Adam, Brian Aquila et al. · Journal of Medicinal Chemistry · 2013 · 115 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

PKC-θ-Deficient Mice Are Protected from Th1-Dependent Antigen-Induced Arthritis

Aileen M. Healy, Elena S. Izmailova, Michael Fitzgerald et al. · The Journal of Immunology · 2006 · 106 citations

Medicine, Immunology, Molecular Biology +16

BET Bromodomain Inhibition Cooperates with PD-1 Blockade to Facilitate Antitumor Response in <i>Kras</i> -Mutant Non–Small Cell Lung Cancer

Dennis O. Adeegbe, Shengwu Liu, Maureen M. Hattersley et al. · Cancer Immunology Research · 2018 · 103 citations · Full text

Medicine, Oncology, Pharmacology +17