Maureen M. Hattersley

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Chaoyang Sun, Jun‐Jie Yin, Yong Fang et al. · Cancer Cell · 2018 · 295 citations · Full text

Homologous Recombination Deficiency, Engineering, Molecular Biology +6

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies

Garrett W. Rhyasen, Maureen M. Hattersley, Yi Yao et al. · Molecular Cancer Therapeutics · 2016 · 147 citations · Full text

Azd5153 Exposure, Pathology, Pharmacotherapy +17

Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)

Edward J. Hennessy, Ammar Adam, Brian Aquila et al. · Journal of Medicinal Chemistry · 2013 · 112 citations · Full text

Compound 14, Apoptosis, Cell Death +18

PKC-θ-Deficient Mice Are Protected from Th1-Dependent Antigen-Induced Arthritis

Aileen M. Healy, Elena S. Izmailova, Michael Fitzgerald et al. · The Journal of Immunology · 2006 · 104 citations

Immunology, Immune Regulation, Pathology +17

BRD4 facilitates replication stress-induced DNA damage response

Jingwen Zhang, Austin Dulak, Maureen M. Hattersley et al. · Oncogene · 2018 · 100 citations · Full text

Chromatin, Genome Instability, Dna Damage +5