Andrew Mitchinson

Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-<i>a</i>]phthalazines as GABA_AReceptor Agonists at the α₃Subunit

Michael G. N. Russell, Robert W. Carling, John Atack et al. · Journal of Medicinal Chemistry · 2005 · 61 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

7-(1,1-Dimethylethyl)-6-(2-ethyl-2 <i>H</i> -1,2,4- triazol-3-ylmethoxy)-3-(2-fluorophenyl)- 1,2,4-triazolo[4,3- <i>b</i> ]pyridazine:  A Functionally Selective γ-Aminobutyric Acid _A (GABA _A ) α2/α3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models

Robert W. Carling, Andrew Madin, Alec Guiblin et al. · Journal of Medicinal Chemistry · 2005 · 54 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Protecting-group strategies for the synthesis of N  4-substituted and N  1,N  8-disubstituted spermidines, exemplified by hirudonine

Bernard T. Golding, Andrew Mitchinson, W. Clegg et al. · Journal of the Chemical Society Perkin Transactions 1 · 1999 · 21 citations

Natural Sciences, Medicinal Chemistry, Drug Discovery +12

A new class of selective, non-basic 5-HT2A receptor antagonists

T. Ladduwahetty, Amanda L. Boase, Andrew Mitchinson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor

Andrew Mitchinson, John Atack, Peter Blurton et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16