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2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor

Andrew Mitchinson, John Atack, Peter Blurton, Robert W. Carling, José L. Castro, Karen S. Curley, Michael G. N. Russell, George Marshall, Ruth M. McKernan, Kevin W. Moore,

Bioorganic & Medicinal Chemistry Letters · 2004 · 21 citations · 8 references

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8

Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

Uwe Rudolph, Florence Crestani, Dietmar Benke et al. · Nature · 1999 · 1.2K citations

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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

Ruth M. McKernan, T.W. Rosahl, David S. Reynolds et al. · Nature Neuroscience · 2000 · 941 citations

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Pharmacological characterization of a novel cell line expressing human <i>α</i><sub>4</sub><i>β</i><sub>3</sub><i>δ</i> GABA<sub>A</sub> receptors

N. Brown, Julie Kerby, Timothy P. Bonnert et al. · British Journal of Pharmacology · 2002 · 602 citations · Full text

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Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.

Karen L. Hadingham, Peter B. Wingrove, B. Le Bourdellès et al. · Molecular Pharmacology · 1993 · 215 citations · Full text

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Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.

Keith A. Wafford, Paul J. Whiting, J A Kemp · Molecular Pharmacology · 1993 · 154 citations

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