Robert W. Carling

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

Ruth M. McKernan, T.W. Rosahl, David S. Reynolds et al. · Nature Neuroscience · 2000 · 935 citations

Molecular Pharmacology, Psychiatry, Neurophysiology +13

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

Paul D. Leeson, Robert W. Carling, Kevin W. Moore et al. · Journal of Medicinal Chemistry · 1992 · 187 citations · Full text

TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates

John Atack, Keith A. Wafford, Spencer J. Tye et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 187 citations

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

Paul D. Leeson, R. BAKER, Robert W. Carling et al. · Journal of Medicinal Chemistry · 1991 · 144 citations

3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-<i>a</i>]phthalazines and Analogues:  High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1

Robert W. Carling, Kevin W. Moore, Leslie J. Street et al. · Journal of Medicinal Chemistry · 2004 · 135 citations · Full text

Lead Identification, Organic Chemistry, Pharmacotherapy +18